Research: Dr. Saneto’s area of research focus is the detection and treatment of pediatric epilepsies caused by mitochondrial disease, and in defining the biochemical and molecular mechanism of mitochondrial disease. He is currently a Principal Investigator (PI) of a treatment trial to manage refractory epilepsy associated with mitochondrial disease, as well as a PI for the North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC). He is a PI in a National Institutes of Health-sponsored clinical trial for treatment of the mitochondrial disease pyruvate dehydrogenase deficiency, as well as PI for two studies associated with EPI-743: one for compassionate use in patients with mitochondrial disease at end of life, and another in the treatment of Leigh syndrome.
Patient Care: Families that are dealing with mitochondrial disease are very fortunate to have one of the leading mitochondrial specialists in the country right here in Seattle. Dr. Saneto’s clinical interests are in the areas of epilepsy, EEG-video telemetry and mitochondrial disorders. He has been with Seattle Children’s Hospital since 2001, where he has pioneered patient care for pediatric epilepsy associated with mitochondrial disease. He was recognized as a “Top Doctor” by Seattle Magazine in 2018 and 2019, and has been recognized as one of the Top Doctors in America since 2009. You can read patient testimonials of his excellent care, here.